reservoir


Title: A5386: Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control in the Reservoirs During Analytic Treatment Interruption Purpose: Researchers are looking for ways to get rid of HIV that rests hidden in areas of the body (reservoirs) where current […]

A5386, a clinical trial to control HIV in a new ...   Recently updated !


Title: AIDS 392: TRAILBLAZER, elimination of CCR5 receptors with zinc finger to prevent viral replication, in participants living with HIV Purpose: The main purpose of this study is to test a new type of strategy to treat HIV: giving people living with HIV genetically modified versions of their own CD4+ […]

AIDS 392: TRAILBLAZER, elimination of CCR5 receptors with zinc finger ...



Trailblazer studies gene-editing HIV treatment at 3 sites Dr. Carl Fichtenbaum at our sister site at the University of Cincinnati talks about #Trailblazer, our HIV treatment study using zinc finger nucleases to perform gene editing on cells to reduce the reservoir of HIV infection. Link: https://www.uc.edu/news/articles/2019/08/n20848753.html

Carl Fichtenbaum’s UofC IDRU takes on gene editing to reduce ...


CWRU’s Sékaly Finds HIV Reservoir Vulnerability  Today the Case Daily published an article about exciting developments in purging the reservoir of infected immune cells in people living with HIV, research conducted by our CFAR colleague Rafick-Pierre Sékaly. A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir […]

CWRU researchers find HIV reservoir vulnerability